Constantine I

Constantine I was the first Christian Roman Emperor and helped evolve the empire into a Christian state. He issued a law that forbid marriages between Jews and Christians, and imposed the death penalty on Jewish people who should break this law. Constantine's Edict of Milan in the 4th century caused Jews to lose many rights and were no longer permitted to live in Jerusalem or to proselytize.

Quotes
"In the first place it was decreed unworthy to observe that most sacred festival in accordance with the practice of the Jews; having sullied their own hands with a heinous crime, such bloodstained are as one might expect mentally blind.", Constantine I.

"... it appeared an unworthy thing that in the celebration of this most holy feast we should follow the practice of the Jews, who have impiously defiled their hands with enormous sin, and are, therefore, deservedly afflicted with blindness of soul ... Let us then have nothing in common with the detestable Jewish crowd; for we have received from our Saviour a different way.", Constantine I.